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Does Erivedge (visomodegib) Cause Hair Loss?

Screen Shot 2018-03-20 at 8.22.36 AMErivedge & Hair Loss, Hair Thinning

What is Erivedge (visomodegib)?

Erivedge or visomodegib capsule is a prescription oral chemotherapy medication for adults with basal cell carcinoma skin cancer that has spread to other parts of the body or that has come back after surgery or cannot be treated with surgery or radiation. At Bauman Medical, chemo hair loss expert Dr. Alan Bauman has examined, evaluated and successfully treated patients who have experienced hair loss, baldness, hair thinning and-or alopecia from Erivedge (vismodegib).

What is the Mechanism of Erivedge – vismodegib?

Vismodegib is a Hedgehog Pathway Inhibitor. By disrupting the hedgehog pathway signal which drives cancer cell growth, Erivedge prevents the cancer from growing. Hedgehog pathways may also be responsible for many of the side effects of Erivedge. For example, Sonic Hedgehog signaling is required for hair follicle development in a fetus and for regulating hair follicle growth and cycling in the adult.

What are some known side effects of Erivedge visomodegib?

In addition to loss of taste, muscle pain, muscle spasms, nausea, vomiting, birth defects, fetal death, diarrhea and fatigue, Hair Loss, alopecia, and-or thinning of scalp and body hair is a known side effect of Erivedge visomodegib. Your hair may become thin, brittle, or may fall out when taking Erivedge. This means that hair breakage, shedding and changes in texture of your hair are possible side effects. In addition to scalp hair loss, Erivedge can cause loss of any body hair, including pubic, underarm, legs/arms, eyelashes, eyebrows and nose hairs. It is assumed that interruption of the Hedgehog pathway is a possible cause of changes in hair follicle function and hair fiber production in those taking the cancer drug Erivedge visomodegib.

Hair Loss and Erivedge Medication for Cancer

Hair Loss is the second side effect listed in the FDA-approved label for Erivedge and seems to be one of the more common side effects of this chemotherapy drug.

Is vismodegib hair loss permanent?

All of the details of hair loss due to Erivedge vismodegib are not known. Hair usually starts to regrow after the treatment is completed, but could take months or longer to fully regrow. Accounts of incomplete or partial hair regrowth have been reported.

Screen Shot 2018-03-19 at 3.34.45 PMWhat can be done about temporary hair loss or alopecia with Erivedge?

If vismodegib is causing temporary alopecia or hair loss, the use of a 3D-Printed Cranial Prosthesis or non-surgical medical-grade hair replacement system may be an excellent option. A CNC hair prosthesis functions beyond a typical medical wig or hair replacement system.

What should I do if I have hair loss related to Erivedge?

First, notify your prescribing doctor immediately of any side effects with Erivedge.
If hair loss side effects occur, seek out a qualified, credentialed (ABHRS, FISHRS, IAHRS) and experienced Hair Restoration Physician. Seek out an MD who has the ability to scientifically evaluate, measure and monitor your hair loss and hair regrowth and has access to the best treatments available. Bottom line, ask an expert. You may ask Dr. Alan Bauman a question about Erivedge hair loss and receive information about what to do if you experience hair loss with Erivedge vismodegib.

What kind of treatments will help hair regrowth after Erivedge vismodegib?

As long as hair follicles remain viable and not permanently damaged, treatments such as laser therapy (LaserCap 224 or CapillusRX), PRP Platelet Rich Plasma, Topical Formula 82M Minoxidil as well as nutritionals/supplements for hair support (Viviscal Pro, Nutrafol) may be good options. If some hair follicles are irreversibly damaged in small areas, FUE hair transplantation with SmartGraft, NeoGraft or ARTAS robotic-system may be required to restore coverage. If large numbers of hair follicles over a large area of scalp are damaged and do not respond to therapy, non-surgical hair replacement with CNC 3D-printed hair prosthesis may be an option.

Learn more about hair loss from Erividge visomodegib at https://www.baumanmedical.com/visomodegib-erivedge-hair-loss/

 

 


What is SmartGraft FUE hair transplant?

SmartGraft FUE BaumanMedicalWhat is SmartGraft device for FUE hair transplantation?

SmartGraft™ is the fastest, most advanced hand-held device for minimally-invasive FUE Follicular Unit Extraction hair transplant procedures we have ever used at Bauman Medical, allowing for the individual harvesting of follicular unit grafts directly from the Donor Area of the scalp without leaving a linear scar or “zipper” appearance. Shorter FUE procedure times means reduced risks of graft failure and poor growth quality, as well as enhanced patient comfort. SmartGraft, by Vision Medical, also has a complete microprocessor controlled graft extraction and storage system which reduces the risk of damage to the fragile FUE grafts. 

Many, including North America's #1 Top Hair Restoration Surgeon (Aesthetic Everything), Dr. Alan J. Bauman MD, believe that SmartGraft is simply a better or maybe “smarter!” way to perform a hair transplant. SmartGraft is a breakthrough device that helps hair transplant surgeons and their specialized teams perform FUE or Follicular Unit Extraction hair transplantation. Less invasive than traditional linear "strip" harvesting, Follicular Unit Extraction uses no scalpel, no stitches, no staples in the donor area--allowing for faster healing and less discomfort after transplantation.

What is FUE Follicular Unit Extraction?

Hair transplantation is the redistribution of permanent, living and growing hair follicles from the “Donor” Area into a thinning or balding “Recipient” area of the scalp. FUE is a harvesting technique which is less invasive than traditional strip or linear harvesting which requires no scalpel or stitches in the Donor Area. Recovery from FUE procedures is more comfortable and less restrictive than with linear or strip harvesting. The vast majority of patients require absolutely NO strong pain medications during their recovery and can return to non-impact athletic physical activity in just several days.

Dating back prior to 2002, renowned hair loss expert and ABHRS-certified Hair Restoration Surgeon, Dr. Alan J. Bauman, MD, ABHRS was amongst a handful of surgeons worldwide who helped develop instruments for, as well as pioneer, research, teach and train doctors on the minimally-invasive techniques of FUE. Dr. Bauman was the very first board-certified hair transplant surgeon in North America to routinely use Neograft, a motorized hair transplant system for no-linear-scar hair follicle harvesting, starting in 2007. He was also one of the first physicians to use the FDA-approved ARTAS robotic-assisted FUE system. Since 2002, Dr. Bauman and his surgical team have transplanted more than 2,500,000 follicular units using the FUE technique–making Dr. Bauman one of the most experienced FUE surgeons in the world. FUE is the least invasive hair transplant procedure and leaves absolutely NO linear scar. It has less downtime and less discomfort than traditional “linear” or “strip-harvest” procedures.

Will SmartGraft FUE Hair Transplant Look Natural?

The final naturalness and undetectability of a hair transplant relies primarily on the minimally-invasive FUE harvesting method of grafts as small as a single follicle and the artistic ability of the surgeon who creates the sites where the follicles will be implanted. Your surgeon must understand the bounds of naturalness of the hairline design, as well as the relationship of each and every angle, orientation and position of the transplanted hair so that the end result looks natural, and not transplanted. Dr. Bauman is renowned for his artistic approach to hairline design and meticulous execution in his hair transplant procedures. Read patient reviews and ratings as well as see Dr. Bauman's artistic hairline and other transplant results at BaumanMedical.com.

For more information about SmartGraft for FUE procedures or to see if you are a candidate for this type of hair transplant procedure, ask a question at www.BaumanMedical.com/ask-a-question

To schedule a Virtual Consultation with Dr. Bauman from anywhere in the world, visit https://www.baumanmedical.com/schedule-consultation