Prostaglandin analogues are synthetic ingredients designed to bind to specific prostaglandin receptor sites on cells which then initiate certain types of cellular activity. When it comes to treating glaucoma and the potential for prostaglandin analogues to stimulate eyelash growth, the three of the most well known options are bimatoprost, travoprost, and latanoprost. Among these, bimatoprost (Latisse) is the most well-researched for eyelash growth, though all have the same potential benefits and side effects. To date, systemic side effects have not been reported in the clinical literature.
(Sources: European Journal of Dermatology, November-December 2009, pages 586–587; Experimental Eye Research, April 2009, pages 786–791; Survey of Ophthalmology, November 2008, pages S93–S105; Expert Opinion on Drug Safety, January 2007, pages 45–52; Clinical and Experimental Ophthalmology, November 2006, pages 755–764; and Drugs in Aging, Volume 19, 2002, pages 231–248).
Allergan is currently testing bimatoprost as a potential treatment for scalp hair loss, male and female pattern baldness, otherwise known as androgenetic alopecia. At Bauman Medical Group, we have used latisse/bimatoprost as an 'off label' topical treament for hair regrowth on the scalp and eyebrows with good success, as recently reported by the New York Times.
Technorati Tags: allergan, alopecia, androgenetic, bimatprost, clinical trials, cosmetics, drug, eyebrow, eyebrow regrowth, eyelash, eyelash transplant, fda approval, female hair loss, hair growth, hair loss, latanoprost, male hair loss, new york times, prostaglandin, research, stratagems for hair regrowth, travoprost
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What can an over-the-counter cosmetic 'hair thickening' product actually do for someone with hair loss? Well, as a hair transplant surgeon, I always thought "not much!" However, I've learned over the years that the right haircare and hairstyling products can be VERY helpful for women with thinning hair and also for some men with thinning hair if they have a medium to longer length hairstyle. At Bauman Medical Group, we developed our own "Bauman-MD" line of haircare products including a sulfate-free, color-safe Shampoo and a lightweight UV protectant Conditioner. As stand-alone products, or for use in conjunction with FDA-approved hair regrowth medications or devices that act directly on the follicles to produce better hair growth, small improvements in hair fiber 'performance' can certainly have an impact on hair styling, managability and scalp coverage.
In 2011, we began working with Dr. Jeni Thomas and her team from Procter & Gamble's Pantene Institute, testing their AgeDefy Hair Thickening product in a blinded clinical trial on nearly 100 women with thinning hair. The science supported the action of the product, which was to thicken each individual hair fiber, but what would the results be on our the clinical trial participants after 6 weeks and after 12 weeks?
The results so far have been extremely encouraging, so stay tuned for the final report! See the video below for more information on Pantene Expert Collection AgeDefy Hair Thickening product.
Posted by Dr. Alan J. Bauman, M.D. on March 19, 2013 at 02:11 PM in Hair Research - Future Therapies, News / Media, Science, Womens Hair Loss / Female Hair Restoration | Permalink | Comments (0) | TrackBack (0)
Technorati Tags: agedefy, clinical trial, conditioner, coverage, cure, dr. alan bauman, dr. jeni thomas, essence, expert, follicle, hair care, hair loss, hair transplant, hairstyling, institute, pantene, pg, problem, procter and gamble, product, receding, scalp, shampoo, thickening, thinning, treatment, UV
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If I Had Google Glass - by Dr. Alan J. Bauman, M.D. (American Board of Hair Restoration Surgery)
#ifihadgoogleglass, all could see what I see... that thinning hair and loss can be treated easily!
At Bauman Medical, reviving follicles is what we do... and if you're receding, we’ve got some re-seeding to do!
See live follicles moving from here to there, now producing living, growing hair. “No scalpel, no stitches” we always rant, because Dr. Bauman’s NeoGraft’s not your father's hair transplant! While comfortable and relaxing like on a long airplane ride, FUE patients are psyched because there’s no linear scar to hide.
Our Circles of patients would have more hope and less misery, because with google glass they'd see much more clearly. Hair follicles are transplanted without pain or plugs, eliminating the need for powders, toupees or rugs. Toss out the hairpiece and you’ll be certainly be glad, to get back a real head of hair... just ask my Dad! The transplant is a symphony of art and surgical detail... and it takes a skilled team or it’s doomed to fail. Done right, the resulting hair? So natural, not pluggy... like it was before it was bare.
In the early stages, time is of the essence... time to fight the hair loss fight and raise the defenses. Knowledge helps those those whose hairlines are receding, in order to avoid the lotions/potions that are misleading. Your teenager hair may no longer be there, but that doesn’t mean you can’t anti-age your hair. Thicker, fuller, healthier than it’s been, just add LaserCap, Viviscal and Formula 82M.
Male or female hair loss may be mostly genetic, but you can verify your hair growth with a routine HairCheck. Scientific evaluations and tracking help Hair Coaches and doctors recommend solutions for those with hair lacking. Shave or ‘wig out’ if you want, if you don’t really care--but don’t most scalps look better when they’re growing hair?
Like Nalts and Benson and Ralston and Greek who tweeted, texted, posted and reshared, for all those follically-challenged followers and YouTube’rs who cared. The first YouTube/Live transplant webcast was good no doubt, but wouldn’t it be cool to have a GoogleGlass Hair Transplant Hangout? Glass can help me help those discouraged by their thinning pate, to show them that hope's not lost... it's not too late!
Maybe soon we’ll have cloning, I’m not really sure, but eventually they’ll find it... the ultimate hair loss cure. ‘Til then we’ll use with the medical treatments we have, safe and effective... lightyears beyond Hippocrates’ gooey salve!
See the future: with Google Glass it's almost here... Click ‘+1’ and ‘Share’ if you'd 'like' to enjoy it with a little more hair! ;-)
Posted by Dr. Alan J. Bauman, M.D. on February 28, 2013 at 07:23 AM in Hair Research - Future Therapies, Humor / Comedy, NeoGraft FUE Hair Transplant, Surgical Hair Restoration (Hair Transplantation), Web/Tech | Permalink | Comments (0) | TrackBack (0)
Technorati Tags: 82m, alopecia, art, bauman medical, boca raton, comedy, contest, dr alan bauman, florida, fue, glass, google, googleglass, hair follicles, hair loss, hair transplant, humor, laser therapy, lasercap, minoxidil, neograft, POV, science, surgery, technology, transplantation
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Posted by Dr. Alan J. Bauman, M.D. on November 15, 2012 at 12:57 PM in Hair Research - Future Therapies, Medical Treatments -- hair loss/hair regrowth (Propecia, Minoxidil, etc), News / Media, Science, Web/Tech | Permalink | Comments (0) | TrackBack (0)
Technorati Tags: 25, abc, bauman medical group, boca raton, bond street salon, broward county, cosmetologist, delray beach, florida, hair check, hair coach, haircoach, lauren donald, measurement, news, palm beach, promo, scientific, stylist, teaser, tool, trichometry, wpbf
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A few years back some studies suggested there was a link between heart disease and male pattern baldness. Today, it seems more information on the relationship between cardiovascular risk and baldness at the top of the head (vertex) is becoming available. Dr. Anne Tybjaerg-Hansen of Copenhagen University Hospital Hair recently presented some new unpublished research on the heart health and baldness connection. Hair has always been a sign of one's health, so here might be one more reason to visit a doctor if you are personally experiencing hair loss or there is a high degree of male pattern baldness in your family.
Joseph Brownstein (FOX NEWS) reports:
A bald patch on the top of your head or a small vertical crease in your earlobe may seem like relatively harmless signs of aging, but a new study says signs like these may signal an increased risk of heart disease.
Danish researchers found that people were 39 percent more likely to have heart disease, and 57 percent more likely to have a heart attack, if they had at least three of these four signs: baldness on top of the head, receded hairline, a crease in the earlobe, and fatty deposits on the eyelids known as xanthelasmata.
The researchers accounted for people's ages in their results.
Therefore, the study shows "looking old for your age, by [having] these aging signs, marks poor cardiovascular health," said study researcher Dr. Anne Tybjaerg-Hansen, a professor and chief physician in the department of clinical biochemistry at Copenhagen University Hospital.
While the exact reason for the links between these signs and heart disease risk remains unclear, the study "validates the common clinical practice that the clinician examines the patient, and often looks at whether a person looks older or younger for her age," Tybjaerg-Hansen said.
The researchers used data from the Copenhagen Heart Study, which included10,885 people who were over the age of 40. Over the 35-year study, 3,401 participants developed heart disease, and 1,708 had a heart attack. Researchers examined six physical features associated with aging, but found that two — gray hair and wrinkles — did not appear to be linked with increased risk of heart problems.
The study included 5,828 men and 5,057 women. When the researchers considered the genders separately, they found that hair loss in women was not linked with an increased risk of heart disease. However, among the 737 men who had a receding hairline, 82 suffered a heart attack, meaning there a 40 percent higher risk in men with hair loss than those without.
Previous research has looked at whether hair loss may be a warning sign of heart disease, but results have been conflicting. Some studies have linked the severity and type of baldness with the risks of heart disease or heart attacks to varying degrees, but others have found no connection. Because the risk of both heart disease and baldness rise with age, it can be difficult for researchers to separate the two in studies.
Tybjaerg-Hansen said the four signs identified in the new study should give clinicians greater incentive to treat patients who have them. "The suggestion is that lifestyle changes and lipid-lowering therapies should be intensified, because their risk is higher," she said.
However, the area needs more research, because "it would be nice to know why these [varying factors] would be associated with increased risk," she said.
Tybjaerg-Hansen said, for example, that hair loss is linked with levels of testosterone in the blood, so the new study suggests the hormone also plays a role in heart disease, but there's "no hard data there at all, [it's] only speculative."
She said the group for whom the new results would raise the greatest concern is men between ages 70 and 79. In this group, 45 percent of those with all four aging signs developed heart disease, versus 31 percent of those with none of the four.
"This study underscores the importance of doing a good physical exam, in addition to any testing we're going to do for risk for heart disease," said Dr. Nieca Goldberg, director of the NYU Center for Women's Health and American Heart Association spokesperson, in a statement in response to the study.
While the researchers adjusted their results to account for other risk factors for heart disease, Goldberg noted that, for example, xanthelasmata is a sign of high cholesterol levels, a traditional risk factor for heart disease.
Goldberg concluded that while the length of the study made the results compelling, doctors "need to continue to monitor our standard testing for heart disease risk, such as measuring cholesterol, blood pressure, glucose for diabetes."
The researchers are presenting their findings today (Nov. 6) at an American Heart Association research conference. The findings have not been published in a scientific journal.
Technorati Tags: alopecia, angina, baldness, CAD, cardiovascular health, cholesterol, coronary artery disease, frontal, hair loss, heart attack, heart disease, high blood pressure, hypertension, male pattern, markers, MI, science, signs, smoking, vertex
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On October 13, 2012 renowned hair transplant surgeon and Course Director, Dr. Pierre Bouhanna, hosted the second International Hair Surgery Master Class (IHSMC) meeting in Paris, France in conjunction with the 8th European Masters of Anti-Aging Medicine Congress (EMAA). In attendance were well over 100 physicians and hair loss experts who listened to a potpourri of lectures on the latest information on the medical and surgical treatment of hair loss. Lectures included the psychological impact of hair loss, basics of medical treatments such as minoxidil, finasteride, laser therapy and nutrition, as well as the latest in hair transplantation techniques and procedures. It was a “quick trip” but one with a well-respected international expert faculty and lots of new information on the treatment of hair loss. A few short hours of Paris sightseeing was possible the day before and the evening after the conference was over.
Dr. Alan J. Bauman presented lectures on a variety of topics including minimally-invasive FUE using NeoGraft (aka S.A.F.E.R. by Medicamat), FUE hair transplant trends, low level laser therapy and hair regrowth (Nutreve and Laser Cap) as well as his protocols for large sessions of FUE transplantation (MEGA-FUE).
Posted by Dr. Alan J. Bauman, M.D. on October 31, 2012 at 10:45 AM in Hair Research - Future Therapies, Laser Therapy, Medical Treatments -- hair loss/hair regrowth (Propecia, Minoxidil, etc), Meetings, Lectures, Conferences & Events, NeoGraft FUE Hair Transplant, News / Media, Surgical Hair Restoration (Hair Transplantation) | Permalink | Comments (0) | TrackBack (0)
Technorati Tags: 2012, abstract, alopecia, bauman, bouhanna, conference, crisostomo, emaa, expert, expo, faculty, france, fue, hair loss, hair restoration, hair transplant, ihsmc, laser cap, lasercap, lecture, low level laser therapy, medicamat, medication, mega fue, neograft, nutreve, october, paris, personal laser, physician, safer, seminar, slideshow, surgery, teaching, training, video
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On October 13, 2012 renowned hair transplant surgeon and Course Director, Dr. Pierre Bouhanna, hosted the second International Hair Surgery Master Class (IHSMC) meeting in Paris, France. In attendance were well over 100 physicians and hair loss experts who listened to a potpourri of lectures on the medical and surgical treatment of hair loss. Lectures included the psychological impact of hair loss, basics of medical treatments, as well as compounded Formula 82M minoxidil, finasteride, PRP, growth factors, laser therapy (Nutreve and LaserCap) and nutritionals, as well as the latest in hair transplantation techniques and procedures.
Some of the highlights of the IHSMC program included:
The 2nd Annual IHSMC was held in conjunction with the 8th European Masters of Anti-Aging Medicine Congress (EMAA) at the Palais des Congrès de Paris, 2 place Porte Maillot, 75017 Paris, France
Dr. Alan J. Bauman (USA) lectured on FUE hair transplants with Neograft/SAFER system, low level laser therapy and FUE hair transplant trends.
Posted by Dr. Alan J. Bauman, M.D. on October 13, 2012 at 07:18 AM in Cosmetic Procedures & Treatments, Eyelash Transplant, Hair Research - Future Therapies, Laser Therapy, Medical Treatments -- hair loss/hair regrowth (Propecia, Minoxidil, etc), Meetings, Lectures, Conferences & Events, NeoGraft FUE Hair Transplant, Surgical Hair Restoration (Hair Transplantation) | Permalink | Comments (0) | TrackBack (0)
Technorati Tags: alan, alopecia, bauman, bouhanna, crisostomo, doctor, emaa, evaluation, fabrio rinaldi, france, fue, gilbert amgar, hair regrowth, ihsmc, laser therapy, lasercap, marc devaris, marcio, medicamat, mega fue, neograft, paris, pierre, prp, rinaldi, safer, surgeon, transplant, treatment
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Posted by Dr. Alan J. Bauman, M.D. on October 08, 2012 at 10:00 PM in Articles/Book Chapters, Hair Research - Future Therapies, Medical Treatments -- hair loss/hair regrowth (Propecia, Minoxidil, etc), Meetings, Lectures, Conferences & Events, Womens Hair Loss / Female Hair Restoration | Permalink | Comments (0) | TrackBack (0)
Technorati Tags: 82m, alopecia, androgenetic, compliance, compounded, dispensing, efficacy, formula, hair loss, minoxidil, off-label, pharmacy, prescription, report, research, rogaine, solution, therapy, topical, treatment, white paper
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Shirley S. Wang (WSJ) reports:
"Much of the research in the field is focused on vitamin D. The receptor—the lock to which the vitamin D key binds—activates hair growth, rather than the vitamin itself, says Marie Demay, a professor of medicine at Harvard Medical School, who pioneered much of this work.
Biochemist Yuko Oda and a team at the VA Medical Center San Francisco and the University of California, San Francisco, recently found a molecule, called MED, that appears to suppress the actions of the receptor. In a study published in December in the Journal of Investigative Dermatology, they found that mice generated more hair after the gene that codes for MED in their skin was knocked out, suggesting a target for gene therapy.
Dr. Demay and colleagues last year found another molecule called LEF1 that also activates the vitamin D receptor, and can do so without the presence of vitamin D. The next step will be to demonstrate that activating the receptor in this way would actually produce hair, says Dr. Demay. If these molecules activate the vitamin D receptor, they change the "fate" of the cells into hair cells, Dr. Oda says. The work was published in the Journal of Biological Chemistry.
Researchers at the University of Tokyo recently added vitamin D supplements to the medium in which they were growing dermal papilla cells, hoping to spur more uncommitted stem cells to become active follicles.
In rats, the scientists found more stem cells were coaxed into becoming follicles when vitamin D was used in the final phase of growing the cells than those not treated, says Kotaro Yoshimura, a professor in the department of plastic surgery who was the senior author on the paper. In addition, more of those follicles matured to produce hair, raising the hope that this might lead to improved hair transplants in the future. The study appeared in the journal Stem Cells Translational Medicine.
Currently, hair transplants can only get single hair from one follicle "but we want to make 1,000 hairs from one follicle," one after the next, says Dr. Yoshimura. They are now teaming up with two other sets of researchers and planning a clinical trial.
A challenge for researchers is that vitamin D has many functions in the body, such as improving bone growth. Taking too much vitamin D can have negative side effects such as calcium accumulation in the blood causing weakness or kidney problems, according to the Mayo Clinic. So it is important that any potential treatment be finely targeted. "We're really aiming to manipulate vitamin D or vitamin D receptors only in the skin," Dr. Oda says."
Read the complete article at http://online.wsj.com/article/SB10000872396390443921504577643442954317340.html
--Results of this reasearch on vitamin D receptors in the skin and what it can actually do for patients with hair loss is, of course, many years off. For today, those with male or female pattern baldness can seek the advice of a hair restoration physician who can provide medical treatments (like Minoxidil 82M, finasteride, bimatoprost/latisse) as well as minimally-invasive hair transplant surgery (NeoGraft FUE). Seek treatments from doctors who routinely perform the procedures and evaluations on a regular basis... not a part-time or newbie physician. Congratulations to the International Society of Hair Restoration Surgery (ISHRS) for the mention in the article. --Dr. Alan Bauman, Bauman Medical Group Hair Transplants and Hair Loss Treatments in Florida
Posted by Dr. Alan J. Bauman, M.D. on September 11, 2012 at 07:17 AM in Hair Research - Future Therapies, Medical Treatments -- hair loss/hair regrowth (Propecia, Minoxidil, etc), News / Media | Permalink | Comments (0) | TrackBack (0)
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